June 17, 2015
15:00 to 18:00	BGA Executive Committee (invitation only), Boardroom 1
19:00 to 21:00	Welcome Reception, Terrace
June 18, 2015
08:00 to 09:00	Registration, Foyer
08:45 to 09:00	Opening and Welcome
09:00 to 10:00	Dobzhansky lecture: Nancy Pedersen, Salon A/B/C
10:00 to 10:30	Break
10:30 to 11:45	Paper Sessions
11:45 to 13:00	Lunch (on your own)
13:00 to 14:00	Plenary: Larry Smarr: Measuring the Human Brain-Gut Microbiome-Immune System Dynamics: a Big Data Challenge, Salon A/B/C
14:00 to 15:15	Paper Sessions
15:15 to 15:45	Break
15:45 to 17:00	Paper Sessions
17:00 to 18:30	Posters, Salon D/E
June 19, 2015
08:00 to 09:00	Registration, Foyer
08:45 to 09:45	Paper Sessions
09:45 to 10:15	Break
10:15 to 11:15	Plenary: Eco de Geus: Genetics of physical activity, Salon A/B/C
11:15 to 12:15	Paper Sessions
12:15 to 13:15	Lunch & BGA Business meeting (lunch provided), Salon A/B
13:15 to 14:15	Plenary: Dr. Felix Frueh: Deriving knowledge from complex genomic and microbiome data for discovery and clinical decision making, Salon A/B/C
14:15 to 15:30	Paper Sessions
15:30 to 16:00	Break
16:00 to 17:15	Paper Sessions
17:30 to 18:30	Paper Sessions
June 20, 2015
08:00 to 09:00	Registration, Foyer
08:45 to 09:45	Paper Sessions
09:45 to 10:05	Break
10:05 to 11:20	Paper Sessions
11:20 to 12:30	Lunch (on your own)
12:30 to 13:30	Plenary: Peggy Farnham: Making sense of GWAS: using epigenomics and genome engineering to understand the functional relevance of SNPs in non-coding regions of the human genome, Salon A/B/C
13:45 to 15:00	Paper Sessions
15:00 to 15:20	Break
15:20 to 16:30	Paper Sessions
16:30 to 18:30	BGA Executive meeting (invitation only), Boardroom 1
18:30 to 21:00	Banquet, Salon C/D/E

Summary of All Sessions

#	Date/Time	Location	Title	Papers
1	June 18, 2015 10:30-11:45	Salon A/B	Symposium: Broken down by age and sex? Gene-environment interplay for health and well-being.	4
2	June 18, 2015 10:30-11:45	Salon C	Personality	5
3	June 18, 2015 10:30-11:45	Gaslamp Room	Physical activity and BMI	4
4	June 18, 2015 14:00-15:15	Salon A/B/C	Quantitative genetic modeling	5
5	June 18, 2015 14:00-15:15	Gaslamp Room	Addictions	4
6	June 18, 2015 15:45-17:00	Salon A/B	Schizophrenia	3
7	June 18, 2015 15:45-17:00	Salon C	Tobacco and Cannabis	4
8	June 18, 2015 15:45-17:00	Gaslamp Room	Parenting	5
9	June 18, 2015 17:00-18:30	Foyer	Poster session	53
10	June 19, 2015 8:45-9:45	Salon A/B	Symposium: Determinants and correlates of physical (in-)activity, part I	3
11	June 19, 2015 8:45-9:45	Salon C	Methods for genome wide analyses	4
12	June 19, 2015 8:45-9:45	Gaslamp Room	Internalizing	4
13	June 19, 2015 11:15-12:15	Salon A/B	Symposium: Determinants and correlates of physical (in-)activity, part II	3
14	June 19, 2015 11:15-12:15	Gaslamp Room	Childhood development	4
15	June 19, 2015 14:15-15:30	Salon A/B/C	Symposium: 50 years of twin studies	4
16	June 19, 2015 14:15-15:30	Gaslamp Room	Traumatic experiences and stress	5
17	June 19, 2015 16:00-17:15	Salon A/B	Symposium: Resuscitating the Louisville Twin Study. A Symposium in Honor of Adam P. Matheny	5
18	June 19, 2015 16:00-17:15	Salon C	Cognitive ability and dementia	4
19	June 19, 2015 16:00-17:15	Gaslamp Room	ADHD and autism	4
20	June 19, 2015 17:30-18:30	Salon A/B	Childhood psychopathology	3
21	June 19, 2015 17:30-18:30	Salon C	New aspects of methods	4
22	June 19, 2015 17:30-18:30	Gaslamp Room	Genes and society	3
23	June 20, 2015 8:45-9:45	Salon A/B	Symposium: Neuroimaging and Genetics, part I	4
24	June 20, 2015 8:45-9:45	Salon C	Academic development	4
25	June 20, 2015 10:05-11:20	Salon A/B	Symposium: Neuroimaging and Genetics, part II	4
26	June 20, 2015 10:05-11:20	Salon C	Development and substance use	4
27	June 20, 2015 10:05-11:20	Gaslamp Room	Depression	4
28	June 20, 2015 13:45-15:00	Salon A/B	Genes, epigenetics and substance use	5
29	June 20, 2015 13:45-15:00	Salon C	Women's health	4
30	June 20, 2015 13:45-15:00	Gaslamp Room	Executive functioning	4
31	June 20, 2015 15:20-16:30	Salon A/B	Symposium: Novel Methods and Recent Results for Enrichment and Pleiotropy in GWAS	4
32	June 20, 2015 15:20-16:30	Salon C	Externalizing	4

 

32 sessions, 178 papers, and 0 presentations with no associated papers

Behavior Genetics Association 45th Annual Meeting
Detailed List of Sessions

                                                                  

Session 1: Symposium: Broken down by age and sex? Gene-environment interplay for health and well-being. June 18, 2015 10:30 to 11:45 Salon A/B
The Interplay of Genes and Environment across Multiple Studies (IGEMS) consortium of ten existing longitudinal twin studies was initiated with a central focus on determining how social context is related to physical functioning (health, functional ability), and psychological functioning (well-being, cognition) in midlife and older ages and on laying the foundation for future studies of gene-environment interplay in late-life functioning. This symposium presents results from analyses focused primarily on age moderation of genetic and environmental components for health and well-being. Sex, country, and construct differences are also explored. In the first presentation, we focus on a harmonized measure of chronic medical illness burden, and note inverted U-shaped curves for genetic and non-shared environmental variance across age for men, but decreasing genetic variance with age for women. The second presentation explores the extent to which smoking, indexed through pack years, modifies genetic and environmental influences on pulmonary function. In the third presentation, we examine age moderation of heritability of loneliness. Finally, we examine age and country differences on genetic influences for measures of marital quality.
Session Chair: Nancy Pedersen, Karolinska Institutet
1. Age moderation of individual differences in chronic medical illness burden
By Margaret Gatz; University of Southern California Andrew Petkus; University of Southern California Carol Franz; University of California San Diego Jaakko Kaprio; University of Helsinki Kaare Christensen; University of Southern Denmark
Presented by: Margaret Gatz, University of Southern California
2. Smoking moderates the importance of genetic and environmental influences on lung function
By Terrie Vasilopoulos; University of Florida Carol Franz; University of California San Diego Deborah Finkel; Indiana University Southeast Matthew McGue; University of Minnesota Jaakko Kaprio; University of Helsinki Nancy Pedersen; Karolinska Institutet
Presented by: Terrie Vasilopoulos, University of Florida
3. Testing for Age Moderation of Heritability of Loneliness across Adulthood
By Dianna Phillips; University of California, Riverside Andrew Petkus; University of Southern California Matthew McGue; University of Minnesota Chandra Reynolds; University of California Riverside
Presented by: Dianna Phillips, University of California, Riverside
(Thompson Award Candidate)
4. Genetic and Environmental Influences on Marital Quality: Examining Age, Country and Construct Differences
By Briana Horwitz; The California State University, Fullerton Kristine Marceau; Brown University and Rhode Island Hospital Jenae Neiderhiser; The Pennsylvania State University iGEMS Consortium; Karolinska Institutet
Presented by: Jenae Neiderhiser, The Pennsylvania State University
Discussant:   Jennifer Harris, National Institute for Public Health
Session 2: Personality June 18, 2015 10:30 to 11:45 Salon C
Session Chair: Dorret Boomsma, VU Amsterdam
1. Rapid genetic (co) variance estimation based on measured SNPs applied to item level data.
By Michel Nivard; VU Conor Dolan; VU University, Amsterdam Wouter Peyrot; NESDA Abdel Abdellaoui; VU University, Amsterdam, the Netherland Jouke-Jan Hottenga; VU University, Amsterdam Christel Middeldorp; VU University Dorret Boomsma; VU Amsterdam
Presented by: Michel Nivard, VU
(Thompson Award Candidate)
2. Prediction from polygenic scores based on GWA of Neuroticism to psychiatric and lifestyle traits
By Dorret Boomsma; VU Amsterdam Stéphanie van den Berg; University of Twente Abdel Abdellaoui; VU University, Amsterdam, the Netherland Eco de Geus; VU University Amsterdam Gonneke Willemsen; VU University Amsterdam Jouke-Jan Hottenga; VU University, Amsterdam Christel Middeldorp; VU University yuri Milaneschi; VU University Medical Center Amsterdam Michel Nivard; VU Jacqueline Vink; Vrije Universiteit Meike Bartels; VU University Amsterdam Gerard Van Grootheest; VU University Medical Center Amsterdam Brenda Penninx; VU University Medical Center Amsterdam Marleen de Moor; VU University Amsterdam
Presented by: Dorret Boomsma, VU Amsterdam
3. Genetic and Environmental Correlations among Five Factor Model Personality Traits and Marital Quality
By Amber Jarnecke; Purdue University Susan South; Purdue University
Presented by: Amber Jarnecke, Purdue University
(Thompson Award Candidate)
4. Genome-wide Association Meta-Analyses for Happiness, Satisfaction with Life and Wellbeing; The Sequel
By Meike Bartels; VU University Amsterdam Aysu Okbay; Erasmus University Rotterdam Jaime Derringer; University of Illinois at Urbana-Champaign Bart Baselmans; VU University Amsterdam Jan-Emmanuel De Neve; University College London Cornelius Rietveld; Erasmus University Rotterdam David Cesarini; New York University Bob Krueger; University of Minnesota Daniel Benjamin; Cornell University Philipp Koellinger; University of Amsterdam
Presented by: Meike Bartels, VU University Amsterdam
5. Individual differences in personality masculinity-femininity: Examining the effects of genes, environment, and prenatal hormone transfer
By Karin Verweij; Karolinska Institutet Miriam Mosing; Karolinska Institute Fredrik Ullén; Karolinska Institute Guy Madison; Umeå University
Presented by: Karin Verweij, Karolinska Institutet
Session 3: Physical activity and BMI June 18, 2015 10:30 to 11:45 Gaslamp Room
Session Chair: Karri Silventoinen, University of Helsinki
1. Changing genetic architecture of BMI from early childhood until the onset of adulthood
By Karri Silventoinen; University of Helsinki
Presented by: Karri Silventoinen, University of Helsinki
2. Cohort Differences in the Etiology of BMI Across the Adult Life Span
By Chandra Reynolds; University of California Riverside Anna Dahl Aslan; Karolinska Institutet Tove Fall; Karolinska Institutet Patrik Magnusson; Karolinska Institutet Nancy Pedersen; Karolinska Institutet
Presented by: Chandra Reynolds, University of California Riverside
3. GENETIC AND ENVIRONMENTAL INFLUENCES ON MOTIVES FOR LEISURE-TIME PHYSICAL ACTIVITY IN FINNISH TWINS
By Sari Aaltonen; University of Helsinki Urho Kujala; University of Jyväskylä Eero Vuoksimaa; University of Helsinki Jaakko Kaprio; University of Helsinki Karri Silventoinen; University of Helsinki
Presented by: Sari Aaltonen, University of Helsinki
4. A new hybrid line may break a selection limit on voluntary wheel running in mice
By Layla Hiramatsu; University of California Riverside Theodore Garland; University of California, Riverside
Presented by: Layla Hiramatsu, University of California Riverside
(Thompson Award Candidate)
Session 4: Quantitative genetic modeling June 18, 2015 14:00 to 15:15 Salon A/B/C
Session Chair: Gitta Lubke, University of Notre Dame, VU University Amsterdam
1. Using pairwise distances as phenotypes in twin-based heritability analyses
By Gitta Lubke; University of Notre Dame, VU University Amsterdam Dorret Boomsma; VU Amsterdam Michael Neale; Virginia Commonwealth University
Presented by: Gitta Lubke, University of Notre Dame, VU University Amsterdam
2. Nonparametric Gene × Environment Estimation: Local Structural Equation Modeling
By Daniel Briley; University of Texas at Austin Kathryn Harden; University of Texas at Austin Timothy Bates; University of Edinburgh Elliot Tucker-Drob; University of Texas at Austin
Presented by: Daniel Briley, University of Texas at Austin
(Thompson Award Candidate)
3. Combining Genomic-Relatedness-Matrix Restricted Maximum Likelihood (GREML) with Structural Equation Modeling in OpenMx
By Robert Kirkpatrick; Virginia Commonwealth University Michael Neale; Virginia Commonwealth University
Presented by: Robert Kirkpatrick, Virginia Commonwealth University
4. A note on moderating covariation between two phenotypes
By Erin Horn; University of Virginia Eric Turkheimer; University of Virginia
Presented by: Erin Horn, University of Virginia
(Thompson Award Candidate)
5. Polyphenotype Multilevel Behavior Genetics Modeling: A step toward unification
By Michael Hunter; University of Oklahoma Health Sciences Center David Bard; University of Oklahoma Health Sciences Center
Presented by: Michael Hunter, University of Oklahoma Health Sciences Center
Session 5: Addictions June 18, 2015 14:00 to 15:15 Gaslamp Room
Session Chair: Wendy Slutske, University of Missouri
1. Childhood Attention-Deficit/Hyperactivity Disorder Symptoms and the Development of Adolescent Alcohol Problems: A Prospective, Population-Based Study of Swedish Twins
By Patrick Quinn; Indiana University Erik Pettersson; Karolinska Institutet Sebastian Lundström; Gothenburg University Henrik Anckarsäter; Gothenburg University Niklas Långström; Karolinska institutet Clara Hellner Gumpert; Karolinska Institutet Henrik Larsson; Karolinska Institutet Paul Lichtenstein; Karolinska Institutet Brian D'Onofrio; Indiana University
Presented by: Patrick Quinn, Indiana University
2. A discordant twin model of the development of alcohol tolerance and problematic use from alcohol initiation over adolescence and young adulthood.
By Arielle Deutsch; University of Missouri-Columbia Andrew Heath; Washington University School of Medicine Michael Lynskey; King’s College Nick G. Martin; QIMR Berghofer Medical Research Institute Wendy Slutske; University of Missouri
Presented by: Arielle Deutsch, University of Missouri-Columbia
3. The Changing Influence of Education and Genetics on the Choice to Continue Smoking in the United States
By Robbee Wedow; University of Colorado Boulder Brooke Huibregtse; University of Colorado at Boulder, Institute for Behavioral Genetics Jason Boardman; University of Colorado
Presented by: Robbee Wedow, University of Colorado Boulder
4. Neighborhood Disadvantage and Gambling Involvement and Disorder: Evidence for Gene-Environment Correlation and Interaction
By Wendy Slutske; University of Missouri Arielle Deutsch; University of Missouri Dixie Statham; University of the Sunshine Coast Nicholas MARTIN; Queensland Institute of Medical Research
Presented by: Wendy Slutske, University of Missouri
Session 6: Schizophrenia June 18, 2015 15:45 to 17:00 Salon A/B
Session Chair: Michael Pogue-Geile, University of Pittsburgh
1. Association and Sequence Fine Mapping of Known Schizophrenia Loci with Psychophysiological Endophenotypes.
By Mengzhen Liu; Institute of Behavior Genetics Scott Vrieze; University of Michigan Stephen Malone; University of Minnesota Uma Vaidyanathan; University of Minnesota Matthew McGue; University of Minnesota Goncalo Abecasis; University of Michigan William Iacono; University of Minnesota
Presented by: Mengzhen Liu, Institute of Behavior Genetics
(Thompson Award Candidate)
2. The Genetic Structure of Cognitive Endophenotypes for Schizophrenia: The Multigenerational Multiplex Genetic Investigation (MGI) of Schizophrenia
By Michael Pogue-Geile; University of Pittsburgh Susan Kuo; University of Pittsburgh Raquel Gur; University of Pennsylvania Laura Almasy; Texas Biomedical Research Institute Reuben Gur; University of Pennsylvania Konasale Prasad; University of Pittsburgh Vishwajit Nimgaonkar; University of Pittsburgh
Presented by: Michael Pogue-Geile, University of Pittsburgh
3. Runs of Homozygosity in the PGC2 Data: No Reliable Association with Schizophrenia
By Emma Johnson; Institute for Behavioral Genetics Doug Bjelland; Institute for Behavioral Genetics Dan Howrigan; University of Colorado Boulder Matthew Keller; University of Colorado at Boulder
Presented by: Emma Johnson, Institute for Behavioral Genetics
(Thompson Award Candidate)
Session 7: Tobacco and Cannabis June 18, 2015 15:45 to 17:00 Salon C
Session Chair: Hermine Maes, Virginia Commonwealth University
1. Passive gene-environment correlation or a developmental gene-environment cascade? Investigating mechanisms of the association of smoking during pregnancy and birth weight using a polygenic scoring approach
By Kristine Marceau; Brown University and Rhode Island Hospital Rohan Palmer; Division of Behavioral Genetics, Rhode Island Hospital & Brown University Jenae Neiderhiser; The Pennsylvania State University Taylor Smith; California Polytechnic State University Valerie Knopik; Rhode Island Hospital
Presented by: Kristine Marceau, Brown University and Rhode Island Hospital
2. Understanding the Relationship between Age of Smoking Onset and Severity of Nicotine Withdrawal Symptoms in Young Adults
By Elizabeth Prom-Wormley; Virginia Commonwealth University Judy Silberg; Virginia Commonwealth University Lindon Eaves; VIPBG, Virginia Commonwealth University Michael Neale; Virginia Commonwealth University Hermine Maes; Virginia Commonwealth University
Presented by: Elizabeth Prom-Wormley, Virginia Commonwealth University
3. Potential Effects of Youth Cannabis Use on Adult Functioning: A Twin Study
By Nayla Hamdi; University of Minnesota Matthew McGue; University of Minnesota William Iacono; University of Minnesota
Presented by: Nayla Hamdi, University of Minnesota
(Thompson Award Candidate)
4. A Multivariate Behavior Genetic Analysis of the Ages of Tobacco, Alcohol, and Cannabis Initiation
By Leah Richmond-Rakerd; University of Missouri Wendy Slutske; University of Missouri Michael Lynskey; King’s College Arpana Agrawal; Washington University Pamela Madden; Washington University Kathleen Bucholz; Washington University Andrew Heath; Washington University School of Medicine Nicholas MARTIN; Queensland Institute of Medical Research
Presented by: Leah Richmond-Rakerd, University of Missouri
(Thompson Award Candidate)
Session 8: Parenting June 18, 2015 15:45 to 17:00 Gaslamp Room
Session Chair: Kelly Klump, Michigan State University
1. Genetic and Environmental Links between Parenting Practices and Child Phenotypes in Early Childhood
By Amanda Cheung; The University of Texas at Austin Kathryn Harden; University of Texas at Austin Elliot Tucker-Drob; University of Texas at Austin
Presented by: Amanda Cheung, The University of Texas at Austin
(Thompson Award Candidate)
2. Family history , the home environment and SES as predictors of response-to-intervention: Project KIDS
By Sara Hart; Florida State University
Presented by: Sara Hart, Florida State University
3. Genetic and Environmental Influences on Parent and Peer Relationships: The Good with the Bad
By Amanda Griffin; Pennsylvania State University Charles Beekman; The Pennsylvania State University Jenae Neiderhiser; The Pennsylvania State University Deborah Gorman-Smith; University of Chicago Kelly Klump; Michigan State University S. Alexandra Burt; Michigan State University
Presented by: Amanda Griffin, Pennsylvania State University
4. Aetiological influences on parents' and children’s shared and distinct perceptions of parenting: a longitudinal study
By Laurie Hannigan; IoPPN, King's College London Tom McAdams; King's College London Robert Plomin; Kings College London Thalia Eley; Institute of Psychiatry
Presented by: Laurie Hannigan, IoPPN, King's College London
(Thompson Award Candidate)
5. Multivariate analysis of genetic and environmental influences on parenting in adolescence
By Megan Patterson; University of Texas at Austin Frank Mann; University of Texas at Austin Elliot Tucker-Drob; University of Texas at Austin Kathryn Harden; University of Texas at Austin
Presented by: Megan Patterson, University of Texas at Austin
(Thompson Award Candidate)
Session 9: Poster session June 18, 2015 17:00 to 18:30 Foyer
Session Chair: Jaakko Kaprio, University of Helsinki
1. The Relationship between Teacher-student relationship and Academic-related Boredom: MAOA Gene as a Moderator
By Yangyang Liu
Presented by: Yangyang Liu,
2. Toddler Developmental Maturity: Heritability and Prenatal and Postnatal Adversity
By Amanda Meachum; Arizona State University Reagan Breitenstein; Arizona State University Kathryn Lemery-Chalfant; Arizona State University Carlos Valiente; Arizona State University
Presented by: Amanda Meachum, Arizona State University
3. DZA Twins Conceived via Identical Double Embryo Donors: Behavioral Features of Three Infant Pairs Raised in Different Countries
By Nancy Segal; CSU Fullerton Amanda Killian; CSU Fullerton
Presented by: Nancy Segal, CSU Fullerton
4. The Etiology of Executive Functioning in Early Childhood
By Lauren Micalizzi; Boston University Kimberly Saudino; Boston University
Presented by: Lauren Micalizzi, Boston University
5. Genetic Overlap between Neuropsychiatric Problems in Childhood and Psychotic Experiences in Adolescence and Emerging Adulthood
By Martin Cederlöf; Karolinska Institutet Erik Pettersson; Karolinska Institutet Amir Sariaslan; Karolinska Institutet Henrik Larsson; Karolinska Institutet Per Östberg; Karolinska Institutet Ian Kelleher; Royal college of surgeouns in Ireland Niklas Långström; Karolinska institutet Henrik Anckarsäter; Gothenburg University Clara Hellner Gumpert; Karolinska Institutet Sebastian Lundström; Gothenburg University Paul Lichtenstein; Karolinska Institutet
Presented by: Martin Cederlöf, Karolinska Institutet
6. Nonshared environmental influences on social aggression: monozygotic twin differences in parental control
By Brooke Slawinski; Michigan State University S. Alexandra Burt; Michigan State University Kelly Klump; Michigan State University
Presented by: Brooke Slawinski, Michigan State University
7. Genetic and Environmental Influences on Toddler Negative Emotionality, Dysregulation, Problem Behaviors, and Competence.
By Olivia Cooke; Arizona State University Sierra Clifford; Arizona State University Carlos Valiente; Arizona State University Kathryn Lemery-Chalfant; Arizona State University
Presented by: Olivia Cooke, Arizona State University
8. Genetic and Environmental Influences on Longitudinal Changes in Functional Biological Age
By Ola Sternäng; School of Health Sciences, Jönköping University Deborah Finkel; Indiana University Southeast Åke Wahlin; School of Health Sciences, Jönköping University
Presented by: Ola Sternäng, School of Health Sciences, Jönköping University
9. Associations between fetal growth and self-perceived health throughout adulthood: A co-twin control study.
By Miriam Mosing; Karolinska Institute Margaret Gatz; University of Southern California Jenae Neiderhiser; The Pennsylvania State University Nancy Pedersen; Karolinska Institutet
Presented by: Miriam Mosing, Karolinska Institute
10. Midlife Cognitive Functioning: Adaptation to Stress and Apolipoprotein E, Interleukin 6, and C-Reactive Protein Genes
By Ryan Barclay; Arizona State University Kathryn Lemery-Chalfant; Arizona State University Mary Davis; Arizona State University Alex Zautra; Arizona State University
Presented by: Ryan Barclay, Arizona State University
11. Prenatal alcohol exposure and ADHD: A prospective extended children-of-twins study
By Espen Eilertsen; Norwegian institute of public health Line Gjerde; Norwegian Institue of Public Health Ted Reichborn-Kjennerud; Norwegian Institute of Public Health Eivind Ystrom; Norwegian Institute of Public Health
Presented by: Espen Eilertsen, Norwegian institute of public health
12. Common etiology between Attention Deficit/Hyperactivity Disorder and abnormal body mass index
By Qi Chen; Karolinska Institutet Ralf Kuja-Halkola; Karolinska Institutet Paul Lichtenstein; Karolinska Institutet Henrik Larsson; Karolinska Institutet
Presented by: Qi Chen, Karolinska Institutet
13. Does perfectionism drive membership into weight-focused peer groups? A co-twin control design investigating potential selection effects
By Shannon O'Connor; Michigan State University S. Alexandra Burt; Michigan State University Kelly Klump; Michigan State University
Presented by: Shannon O'Connor, Michigan State University
14. Familial liability for eating disorders and suicidal behavior: a population-based study in Sweden
By Shuyang Yao; Karolinska Institutet Ralf Kuja-Halkola; Karolinska Institutet Laura Thornton; University of North Carolina at Chapel Hill Cristin Runfola; University of North Carolina at Chapel Hill Brian D'Onofrio; Indiana University Cynthia Bulik; University of North Carolina at Chapel Hill Henrik Larsson; Karolinska Institutet
Presented by: Shuyang Yao, Karolinska Institutet
15. Parent-offspring similarity of drinking behaviors in a longitudinal twin sample
By Gretchen Saunders; University of Minnesota - Twin Cities Matthew McGue; University of Minnesota
Presented by: Gretchen Saunders, University of Minnesota - Twin Cities
16. Genome Wide Association Study of Cocaine Dependence and Related Traits in a High-Risk Sample
By Spencer Huggett Michael Stallings; University of Colorado
Presented by: Spencer Huggett,
17. Genetic and environmental influences on the relation between ADHD-like traits and internalizing problems: a Chinese child twin study
By Tian-jiao Chen; Peking University Henrik Larsson; Karolinska Institutet Paul Lichtenstein; Karolinska Institutet Zheng Chang; Karolinska Institutet
Presented by: Zheng Chang, Karolinska Institutet
18. Genome-wide Association Study of Specific Psychotic Experiences in Adolescence
By Oliver Pain; Birkbeck, University of London Frank Dudbridge; London School of Hygiene and Tropical Medicine Robert Plomin Angelica Ronald; Birkbeck/Institute of Psychiatry
Presented by: Oliver Pain, Birkbeck, University of London
19. Genetic and Environmental Influences on Early Social Competence: Moderation by Childcare
By Sierra Clifford; Arizona State University Kathryn Lemery-Chalfant; Arizona State University Carlos Valiente; Arizona State University
Presented by: Sierra Clifford, Arizona State University
20. Genes for Good: Wearable Sensors and User Engagement
By David Brazel; University of Colorado Boulder Maia Frieser; University of Colorado Boulder Johanna Forster; University of Michigan Kevin Li; University of Michigan Gregory Zajac; University of Michigan Katharine Brieger; University of Michigan Goncalo Abecasis; University of Michigan Scott Vrieze; University of Michigan
Presented by: David Brazel, University of Colorado Boulder
(Thompson Award Candidate)
21. Environmental and Genetic Influences on Effortful Control in Early Childhood: A Study in Adopted Children and Their Tamilies
By Yayouk Willems; VU University Amanda Griffin; Pennsylvania State University Meike Bartels; VU University Amsterdam Catrin Finkenauer; VU university Amsterdam David Reiss; Yale Daniel Shaw; University of Pittsburgh Jody Ganiban; George Washington University Misaki Natsuaki; University of California-Riverside Leslie Leve; University of Oregon Jenae Neiderhiser; The Pennsylvania State University
Presented by: Yayouk Willems, VU University
22. Genome wide variation predicts number of lifetime sexual partners: A polygenic score approach
By Brooke Huibregtse; University of Colorado at Boulder, Institute for Behavioral Genetics Michael Stallings; University of Colorado
Presented by: Brooke Huibregtse, University of Colorado at Boulder, Institute for Behavioral Genetics
23. Does marital adjustment moderate genetic and environmental influences on parenting?
By Emily LeDonne; The Pennsylvania State University Ashlea M. Klahr; The University of Chicago Jenae Neiderhiser; The Pennsylvania State University Kelly Klump; Michigan State University Deborah Gorman-Smith; University of Chicago S. Alexandra Burt; Michigan State University
Presented by: Emily LeDonne, The Pennsylvania State University
24. Partial Replication of Two Rumination-related Candidate Gene Studies.
By Carol Van Hulle; University of Wisconsin-Madison Sierra Clifford; Arizona State University Mollie Moore; University of Wisconsin-Madison Kathryn Lemery-Chalfant; Arizona State University Hill Goldsmith; University of Wisconsin
Presented by: Carol Van Hulle, University of Wisconsin-Madison
25. Effects of early-life exposure to Western diet on adult activity levels and associated behavioral and physiological traits
By Jarren Kay; University of California Riverside Ralph Albuquerque; University of California Riverside Gerald Claghorn; University of California Riverside Layla Hiramatsu; University of California Riverside Jennifer Singleton; University of California Riverside Zoe Thompson; University of California Riverside James Colbath; University of California Riverside Brett Ho; University of California Riverside Brittany Ho; University of California Riverside Gabriela Sanchez; University of California Riverside Danny Thai; University of California Riverside Theodore Garland; University of California, Riverside
Presented by: Jarren Kay, University of California Riverside
26. Social environment affects heritability of smoking persistence. Comparison between two twin cohorts born before and after the 70's pro-smoking change in Spain
By Laura Mezquita; Universitat Jaume I Juan Sanchez-Romera; University of Murcia Manuel Ibañez; Universitat Jaume I Lucía Colodro Conde; QIMR Berghofer Medical Research Institute Generos Ortet; Universitat Jaume I Juan Ordonana; University of Murcia
Presented by: Lucía Colodro Conde, QIMR Berghofer Medical Research Institute
27. Early family environment moderates the environmental contributions to anxiety in later life.
By Andrew Petkus; University of Southern California Lewina Lee; Boston University Schools of Medicine and Public Health
Presented by: Andrew Petkus, University of Southern California
28. Longitudinal Links Between Callous-Unemotional Traits and Parent Negativity
By Megan Flom; Boston University Kimberly Saudino; Boston University
Presented by: Megan Flom, Boston University
29. Meta-analysis of the association between birth weight and ADHD
By Aspen Makkar; California Polytechnic State University ryan manning; California Polytechnic University Arielle plavnick; California Polytechnic State University Michael Vargas; California Polytechnic State University Olivia Einbund; California Polytechnic State University Valerie Knopik; Rhode Island Hospital Taylor Smith; California Polytechnic State University
Presented by: Taylor Smith, California Polytechnic State University
30. Parental depression and prenatal risk influences on child social competence: Understanding genetic and environmental influences
By Amanda Ramos; Penn State University Amanda Griffin; Pennsylvania State University Chang (Cecilia) Liu; Penn State University Daniel Shaw; University of Pittsburgh Leslie Leve; University of Oregon Jody Ganiban; George Washington University Misaki Natsuaki; University of California-Riverside Jenae Neiderhiser; The Pennsylvania State University
Presented by: Amanda Ramos, Penn State University
31. Age and Severity of Alcohol and Marijuana Initiation: Effect on P300 Amplitude in a Sample of Twins
By Claire Gorey Marina Bornovalova; University of South Florida Steve Malone; University of Minnesota William Iacono; University of Minnesota Matthew McGue; University of Minnesota
Presented by: Claire Gorey,
32. Mutual Influences between Adopted Children’s Anger and Adoptive Parents Structured Parenting: A Prospective Adoption Study
By Chang (Cecilia) Liu; Penn State University Amanda Ramos; Penn State University Ginger Moore; Penn State University Leslie Leve; University of Oregon Daniel Shaw; University of Pittsburgh Jody Ganiban; George Washington University David Reiss; Yale Misaki Natsuaki; University of California-Riverside Jenae Neiderhiser; The Pennsylvania State University
Presented by: Chang (Cecilia) Liu, Penn State University
33. Genetic and environmental influences on self-control, grit, and conscientiousness: Results from Japanese adolescent twins
By Yusuke Takahashi; Kyoto University Shinji Yamagata; Kyushu University Juko Ando; Keio University
Presented by: Yusuke Takahashi, Kyoto University
34. Genetic and Environmental Contributions to Children’s High Intensity Physical Activity: Evidence of evocative rGE?
By Frances Mallari; George Washington University Diane Mitchell; Penn State Leslie Leve; University of Oregon Jenae Neiderhiser; The Pennsylvania State University David Reiss; Yale Misaki Natsuaki; University of California-Riverside Daniel Shaw; University of Pittsburgh Jody Ganiban; George Washington University
Presented by: Frances Mallari, George Washington University
(Thompson Award Candidate)
35. Heritability and longitudinal stability of planning and behavioral disinhibition based on the Porteus Maze Test
By Marcella May; University of Southern California Catherine Tuvblad; USC Laura Baker; University of Southern California Adrian Raine; University of Pennsylvania
Presented by: Marcella May, University of Southern California
36. Genetic and environmental influences on adolescent and young adult smoking initiation: Examining heterogeneity by race
By Cristina Bares; Virginia Commonwealth University Hermine Maes; Virginia Commonwealth University
Presented by: Cristina Bares, Virginia Commonwealth University
37. Comparing Relative Telomere Length between Buccal and Leukocyte Derived DNA
By Casey Finnicum; Avera Institute for Human Genetics Zachary Weber; Avera Institute for Human Genetics Jason Petersen; Avera Institute for Human Genetics Veryan Codd; University of Leicester Conor Dolan; VU University, Amsterdam Gareth Davies; Avera Institute for Human Genetics Erik Ehli; Avera Institute for Human Genetics Gonneke Willemsen; VU University Amsterdam Dorret Boomsma; VU Amsterdam
Presented by: Casey Finnicum, Avera Institute for Human Genetics
38. Moderation of personality by positive life events.
By Jason Scicchitano; University of Illinois at Urbana-Champaign Jaime Derringer; University of Illinois at Urbana-Champaign
Presented by: Jason Scicchitano, University of Illinois at Urbana-Champaign
39. Understanding Nonlinear Predictors of Follow-Up Participation of Twins in Project Talent Twin and Sibling Study
By Randy Bautista; University of Southern California John McArdle; University of Southern California Deanna Lyter; American Institutes for Research Susan Lapham; American Institutes for Research Carol Prescott; University of Southern California
Presented by: Randy Bautista, University of Southern California
40. Working Memory in Relation to Math and Reading: A Twin Study
By David Katz; Case Western Reserve University Stephen Petrill; The Ohio State University Lee Thompson; Case Western Reserve University
Presented by: David Katz, Case Western Reserve University
41. Phenotypic differences in facial features of individuals with the 16p11.2 copy number variant
By Tim Pang; UCSD
Presented by: Tim Pang, UCSD
42. A longitudinal look at parent-offspring similarity in personality
By Bridget Carey; University of Minnesota William Iacono; University of Minnesota Matthew McGue; University of Minnesota
Presented by: Bridget Carey, University of Minnesota
43. The stability of cognitive performance across time in a longitudinal twin design
By Shandell Pahlen; University of Minnesota Matthew McGue; University of Minnesota Chandra Reynolds; University of California Riverside
Presented by: Shandell Pahlen, University of Minnesota
44. Serotonin-mediated central fatigue underlies increased endurance in mice that have been selectively bred for high voluntary wheel running
By Gerald Claghorn; University of California Riverside
Presented by: Gerald Claghorn, University of California Riverside
45. Estimating Heritability of Reactive and Proactive Aggression: An Item Response Theory Approach
By Shannon Potts; University of Southern California Catherine Tuvblad; USC Laura Baker; University of Southern California Adrian Raine; University of Pennsylvania
Presented by: Shannon Potts, University of Southern California
46. Genetic and Environmental Influences on Math Achievement and Math Cognition Measures: A Twin Study
By Carol Gross; Case Western Reserve University Lee Thompson; Case Western Reserve University Stephen Petrill; The Ohio State University
Presented by: Carol Gross, Case Western Reserve University
47. The impact of culture on genetic and environmental contributions to externalizing behavior during adolescence.
By Jody Ganiban; George Washington University Misaki Natsuaki; University of California-Riverside Kristine Marceau; Brown University and Rhode Island Hospital Xinying Li; Chinese Academy of Sciences David Reiss; Yale Jenae Neiderhiser; The Pennsylvania State University
Presented by: Jody Ganiban, George Washington University
48. Locating Participants Using Sibling and Family Relationships in the Project Talent Twin and Sibling Study
By Deanna Lyter Achorn; American Institutes for Research Carol Prescott; University of Southern California Danielle Battle; American Institutes for Research Ashley Kaiser; American Institutes for Research Susan Lapham; American Institutes for Research George Rebok; American Institutes for Research, Johns Hopkins Bloomberg School of Public Health
Presented by: Deanna Lyter Achorn, American Institutes for Research
49. Heritability of Reading Comprehension: A Meta-Analysis
By Callie Little; Florida State University Sara Hart; Florida State University
Presented by: Callie Little, Florida State University
50. Whole Genome Sequence Analysis of Cannabis Dependence in the UCSF Family Alcoholism Study
By Ian Gizer; University of Missouri Chris Bizon; Renaissance Computing Institute David Gilder; The Scripps Research Institute Cindy Ehlers; The Scripps Research Institute Kirk Wilhelmsen; University of North Carolina-Chapel Hill
Presented by: Ian Gizer, University of Missouri
51. Particulate Air Pollutants, Delinquency, and Aggressive and Behaviors of Adolescents in Southern California: A Longitudinal Analysis
By Laura Baker; University of Southern California Catherine Tuvblad; USC
Presented by: Laura Baker, University of Southern California
52. Higher rates of DZ twinning in a 21st century birth cohort
By Sally Ann Rhea; CU Boulder Robin Corley; University of Colorado Boulder John Hewitt; University of Colorado Boulder
Presented by: Sally Ann Rhea, CU Boulder
53. Exome sequencing of mesial temporal lobe epilepsy with hippocampal sclerosis in parent-offspring trios
By Stacey Cherny; The University of Hong Kong
Presented by: Stacey Cherny, The University of Hong Kong
Session 10: Symposium: Determinants and correlates of physical (in-)activity, part I June 19, 2015 8:45 to 9:45 Salon A/B
Regular physical activity is a key contributor to health, whereas a sedentary lifestyle is cited as one of the main causes for the most influential non-transmittable diseases of our time, including diabetes, heart disease and cancer. It is important to understand individual differences in the determinants and correlates of physical (in-)activity to develop successful interventions that improve health on a population level. This symposium roughly consists of two parts. In the first part, twin-family models will be applied to exercise data of 7- to 18- year old twins, their siblings and parents to get a better understanding of the relative contribution of genes and the environment to variance in exercise behavior and its stability over time. This study will be complemented by two talks on animal models looking at the innate activity drive of rodents and its association with SNP data and whole-genome sequence data. The second part of the symposium includes three talks on commonly studied covariates of physical activity. First, the longitudinal association between physical inactivity and body mass index will be reported. Next, a twin study will be presented in which habitual exercise and objectively measured fitness was associated with depressive symptoms. Finally, the extended twin design will be used to find the sources of variation in affective responses to exercise in a healthy adolescent population. In sum, this symposium features the latest research on physical (in-)activity and highlights the important contribution of genetics to unravel the etiology of this behavior.
Session Chairs:
1. Charlotte Huppertz, VU University
2. Nienke Schutte, VU University Amsterdam
1. Exercise behavior in childhood and adolescence: Age-moderation and temporal stability
By Charlotte Huppertz; VU University Meike Bartels; VU University Amsterdam Catherina van Beijsterveldt; VU University Amsterdam Gonneke Willemsen; VU University Amsterdam Dorret Boomsma; VU Amsterdam Jim Hudziak; UVM Eco de Geus; VU University Amsterdam
Presented by: Charlotte Huppertz, VU University
(Thompson Award Candidate)
2. Born to Run: replicated selective breeding for high levels of voluntary exercise in house mice
By Theodore Garland; University of California, Riverside
Presented by: Theodore Garland, University of California, Riverside
3. Born to Run: 2. genetic architecture of voluntary exercise in replicated selection lines of house mice
By Liran Yadgary; University of North Carolina - Chapel Hill Daniel Pomp; University of North Carolina - Chapel Hill George Weinstock; Jackson Laboratory for Genomic Medicine, Farmington Theodore Garland; University of California, Riverside Fernando Pardo Manuel de Villena; University of North Carolina - Chapel Hill
Presented by: Liran Yadgary, University of North Carolina - Chapel Hill
Session 11: Methods for genome wide analyses June 19, 2015 8:45 to 9:45 Salon C
Session Chair: Greg Carey, University of Colorado
1. Phenome-wide analysis of genome-wide polygenic scores
By Eva Krapohl; King's College London Robert Plomin; Kings College London
Presented by: Eva Krapohl, King's College London
(Thompson Award Candidate)
2. Gene–Environment Interactions in Biologically Proximate and Distal Traits
By Ronald de Vlaming; Erasmus University Rotterdam Aysu Okbay; Erasmus University Rotterdam Philipp Koellinger; University of Amsterdam Cornelius Rietveld; Erasmus University Rotterdam Daniel Benjamin; Cornell University David Cesarini; New York University Patrick Groenen; Erasmus University Rotterdam Roy Thurik; Erasmus University Rotterdam
Presented by: Ronald de Vlaming, Erasmus University Rotterdam
3. Challenges and Solutions for the Use of Cognitive Data in Genetically Informative Research
By Matthew Panizzon; University of California San Diego Eero Vuoksimaa; University of Helsinki Michael Lyons; Boston University William Kremen; University of California San Diego and VA SD Center of Excellence for Stress and Mental Health
Presented by: Matthew Panizzon, University of California San Diego
4. GCTAx: Extended genome-wide complex trait analysis.
By Greg Carey; University of Colorado Beate St. Pourcain; University of Bristol David Evans; Bristol University Lindon Eaves; VIPBG, Virginia Commonwealth University
Presented by: Greg Carey, University of Colorado
Session 12: Internalizing June 19, 2015 8:45 to 9:45 Gaslamp Room
Session Chair: Paul Lichtenstein, Karolinska Institutet
1. Sex differences in genetic influences on comorbidity between anxiety disorders and personality disorders: A twin study.
By Audun Welander-Vatn; Norwegian Institute of Public Health Eivind Ystrom; Norwegian Institute of Public Health Kristian Tambs; Norwegian Institute of Public Health Jack Hettema; Virginia Institute for Psychiatric and Behavioral Genetics Michael Neale; Virginia Commonwealth University Kenneth Kendler; Virginia Commonwealth University Ted Reichborn-Kjennerud; Norwegian Institute of Public Health Gun Peggy Knudsen; Norwegian Institute of Public Health
Presented by: Audun Welander-Vatn, Norwegian Institute of Public Health
(Thompson Award Candidate)
2. Choosing a powerful depression phenotype: Trajectories of anxiety and depression between age 7 and age 18 and the influence of genetic factors in Dutch twins
By Patrick Miller; University of Notre Dame Brad Verhulst; Virginia Institute of Psychiatric and Behavioral Genetics Meike Bartels; VU University Amsterdam Toos van Beijsterveldt; VU University Amsterdam Gonneke Willemsen; VU University Amsterdam Dorret Boomsma; VU Amsterdam Christel Middeldorp; VU University Gitta Lubke; University of Notre Dame, VU University Amsterdam
Presented by: Patrick Miller, University of Notre Dame
(Thompson Award Candidate)
3. Examining the relationship between single motherhood and depression: direction of causation, moderators, and cross-cultural comparisons
By Diana Dinescu; University of Virginia Robert Emery; University of Virginia Erin Horn; University of Virginia Eric Turkheimer; University of Virginia
Presented by: Diana Dinescu, University of Virginia
(Thompson Award Candidate)
4. The Intergenerational Transmission of Suicidal Behavior: A Children of Twins and Siblings Study
By Lauren Bramson; Indiana University, Bloomington Martin Rickert; Indiana University Quetzal Class; Indiana University Henrik Larsson; Karolinska Institutet Paul Lichtenstein; Karolinska Institutet Brian D'Onofrio; Indiana University
Presented by: Lauren Bramson, Indiana University, Bloomington
Session 13: Symposium: Determinants and correlates of physical (in-)activity, part II June 19, 2015 11:15 to 12:15 Salon A/B
Session Chairs:
1. Nienke Schutte, VU University Amsterdam
2. Charlotte Huppertz, VU University
1. The association of physical inactivity and body mass index in the Finnish twin pairs discordant for their leisure-time physical activity during a 35-year follow-up
By Maarit Piirtola; University of Helsinki Jaakko Kaprio; University of Helsinki Katja Waller; University of Jyväskylä Kauko Heikkilä; University of Helsinki Markku Koskenvuo; University of Helsinki Pia Svedberg; Karolinska Institutet Karri Silventoinen; University of Helsinki Urho Kujala; University of Jyväskylä Annina Ropponen; Finnish Institute of Occupational Health
Presented by: Maarit Piirtola, University of Helsinki
2. Genetic and Environmental Interplay in the Association between Depression and Regular Exercise and Physical Fitness
By Wendy Johnson; University of Edinburgh Erik Mortensen; University of Copenhagen Kirsten Kyvik; University of Southern Denmark
Presented by: Wendy Johnson, University of Edinburgh
3. Differences in acute affective responses to exercise
By Nienke Schutte; VU University Amsterdam Ineke Nederend; VU University Amsterdam Jim Hudziak; UVM Meike Bartels; VU University Amsterdam Eco de Geus; VU University Amsterdam
Presented by: Nienke Schutte, VU University Amsterdam
(Thompson Award Candidate)
Session 14: Childhood development June 19, 2015 11:15 to 12:15 Gaslamp Room
Session Chair: Timothy Bates, University of Edinburgh
1. IToR – a novel, prospective extended children of twins study
By Line Gjerde; Norwegian Institue of Public Health Espen Eilertsen; Norwegian institute of public health Ted Reichborn-Kjennerud; Norwegian Institute of Public Health Eivind Ystrom; Norwegian Institute of Public Health
Presented by: Line Gjerde, Norwegian Institue of Public Health
2. Infant Brain Development: Genetic and environmental influences from birth to 2 years of age
By Timothy Bates; University of Edinburgh John Gilmore; Department of Psychiatry, University of North Carolina-Chapel Hill Michael Neale; Virginia Commonwealth University
Presented by: Timothy Bates, University of Edinburgh
3. The parameter space of a Nuclear-Twin-Family model of early childhood reading
By William Coventry; University of New England Amelia Vogel; University of New England Robin Corley; University of Colorado Boulder richard olson; University of Colorado stefan samuelsson; Linköping University Brian Byrne; University of New England
Presented by: William Coventry, University of New England
4. General psychopathology and parenting as genetic and environmental influences on trajectories of co-occurring behavior problems in children
By Charles Beekman; The Pennsylvania State University Leslie Roos; University of Oregon Leslie Leve; University of Oregon Daniel Shaw; University of Pittsburgh Jody Ganiban; George Washington University David Reiss; Yale Jenae Neiderhiser; The Pennsylvania State University
Presented by: Charles Beekman, The Pennsylvania State University
Session 15: Symposium: 50 years of twin studies June 19, 2015 14:15 to 15:30 Salon A/B/C
Session Chair: Tinca Polderman, VU University Amsterdam
1. The planning, and Implementation of the National Merit Twin Study
By Robert Nichols; NA
Presented by: Robert Nichols, NA
2. The National Merit Twin Study data and me
By John Loehlin; University of Texas
Presented by: John Loehlin, University of Texas
3. 50 years of twin studies: A meta-analysis of all human traits. Part I
By D Posthuma; VU University Amsterdam Tinca Polderman; VU University Amsterdam Beben Benyamin; Queensland Institute of Medical Research Christiaan De Leeuw; Radboud University Nijmegen
Presented by: D Posthuma, VU University Amsterdam
4. 50 years of twin studies: A meta-analysis of all human traits. Part II
By Tinca Polderman; VU University Amsterdam Beben Benyamin; Queensland Institute of Medical Research Christiaan De Leeuw; Radboud University Nijmegen D Posthuma; VU University Amsterdam
Presented by: Tinca Polderman, VU University Amsterdam
Session 16: Traumatic experiences and stress June 19, 2015 14:15 to 15:30 Gaslamp Room
Session Chair: Elliot Tucker-Drob, University of Texas at Austin
1. Trauma Exposure, Stressful Life Events, and Internalizing and Externalizing Psychopathology: Multivariate Structure and Shared Etiology
By Devon LoParo; Emory University Kerry Ressler; Emory University Irwin Waldman; Emory University
Presented by: Devon LoParo, Emory University
(Thompson Award Candidate)
2. Examining the moderating role of trauma on the genetic and environmental contributions to PTSD symptom clusters
By Chelsea Sawyers; Virginia Commonwealth University Michael Neale; Virginia Commonwealth University Carol Franz; University of California San Diego
Presented by: Chelsea Sawyers, Virginia Commonwealth University
(Thompson Award Candidate)
3. Stressful Life Events and Smoking Behavior in the Transitions to Substance Abuse (TSA) Follow-Up
By Elizabeth Do; Virginia Commonwealth University Hermine Maes; Virginia Commonwealth University
Presented by: Elizabeth Do, Virginia Commonwealth University
(Thompson Award Candidate)
4. Biometric Analysis of Chronic Cortisol in a Socioeconomically Diverse Twin Sample
By Elliot Tucker-Drob; University of Texas at Austin Daniel Briley; University of Texas at Austin Laura Engelhardt; University of Texas at Austin Frank Mann; University of Texas at Austin Megan Patterson; University of Texas at Austin Kathryn Harden; University of Texas at Austin
Presented by: Elliot Tucker-Drob, University of Texas at Austin
5. Gene expression profiles following acute stress exposure in adults with early trauma history
By Robert Kumsta; Ruhr-University Bochum
Presented by: Robert Kumsta, Ruhr-University Bochum
Session 17: Symposium: Resuscitating the Louisville Twin Study. A Symposium in Honor of Adam P. Matheny June 19, 2015 16:00 to 17:15 Salon A/B
The Louisville Twin Study (LTS), conducted over a thirty year period between roughly 1970 to 2000, was unquestionably one of the most important twin studies ever conducted, producing many classic papers in the development of intelligence, temperament and physical growth. The study was probably most remarkable for the longitudinal intensity of its research design. Twins were measured on up to 15 occasions between the ages of three months and eighteen year. Intensive self-report and longitudinal data were also collected on siblings and parents. The study, however, had a somewhat unusual history. Several or the most important investigators died or retired before the study was complete. Very little was published from the study during the last third of its existence, and we have recently discovered that much important data was never recorded. Even the classic, highly cited analyses that emerged from the study were mostly conducted before the availability of modern statistical modeling methods. We have recently received a small grant from the NIA to begin the process or resuscitating the LTS by (a) reconducting some of the classic analyses using modern methods; (b) using the existing data to address contemporary scientific questions, especially concerning gene-environment correlation and regression in the development of cognitive ability; (c) starting the process of rebuilding the database and making it available for analysis by the research community; and (d) laying the groundwork for eventual recontacting of the study participants, who are now middle aged. We will present symposium of papers on these topics, each of them including a briefing on the scope of data that will be available for analysis when the project is complete.
Session Chair: Eric Turkheimer, University of Virginia
1. Applying Latent Growth Curve Models to Developmental Synchronies in Cognitive Development in Louisville Twin Study Data
By Deborah Finkel; Indiana University Southeast Deborah Davis; University of Louisville William Dickens; Northeastern University Eric Turkheimer; University of Virginia
Presented by: Deborah Finkel, Indiana University Southeast
2. Genetic and environmental contributions to behavioral stability during infancy: Revisiting Louisville Twin Study Data
By Deborah Davis; University of Louisville Deborah Finkel; Indiana University Southeast Eric Turkheimer; University of Virginia William Dickens; Northeastern University
Presented by: Deborah Davis, University of Louisville
3. Longitudinal phenotype-environment models in the Louisville Twin Study and their interpretation
By Christopher Beam; University of Virginia Eric Turkheimer; University of Virginia Deborah Davis; University of Louisville
Presented by: Christopher Beam, University of Virginia
(Thompson Award Candidate)
4. A Longitudinal Analysis to Birth Order Contributions to Shared and Non-shared Environment
By Deborah Davis; University of Louisville William Dickens; Northeastern University Deborah Finkel; Indiana University Southeast Rachel Sederberg; Northeastern University Eric Turkheimer; University of Virginia
Presented by: Rachel Sederberg, Northeastern University
(Thompson Award Candidate)
5. Investigating Poverty by Heritability Interactions in the Louisville Twin Study
By Eric Turkheimer; University of Virginia Christopher Beam; University of Virginia Deborah Finkel; Indiana University Southeast Deborah Davis; University of Louisville William Dickens; Northeastern University
Presented by: Eric Turkheimer, University of Virginia
Session 18: Cognitive ability and dementia June 19, 2015 16:00 to 17:15 Salon C
Session Chair: Michael Lyons, Boston University
1. APOE alleles and aging-related memory decline: the tortoise (E2) and the hare (E4)
By Thalida Arpawong; University of Southern California John McArdle; University of Southern California Carol Prescott; University of Southern California
Presented by: Thalida Arpawong, University of Southern California
2. Genetic susceptibility to cardiovascular disease and risk of dementia
By Ida Karlsson; Karolinska Institutet Sara Hägg; Karolinska Institutet Alexander Ploner; Karolinska Institutet Ci Song; Karolinska Institutet Margaret Gatz; University of Southern California Nancy Pedersen; Karolinska Institutet
Presented by: Ida Karlsson, Karolinska Institutet
(Thompson Award Candidate)
3. Genetic influences on neuropsychological traits as assessed by the web-based Computerized Neurocognitive Battery
By Suzanne Swagerman; VU University Amsterdam Eco de Geus; VU University Amsterdam Kees-Jan Kan; VU University Amsterdam Marinka Koenis; University Medical Center Utrecht Rachel Brouwer; University Medical Center Utrecht Hilleke Hulshoff Pol; University Medical Center Utrecht Dorret Boomsma; VU Amsterdam
Presented by: Suzanne Swagerman, VU University Amsterdam
(Thompson Award Candidate)
4. Genetic and Environmental Influences on Stability, Change, and Heterogeneity in General Cognitive Ability over Four Decades of Adulthood
By Michael Lyons; Boston University Matthew Panizzon; University of California San Diego Carol Franz; University of California San Diego Kristen Jacobson; The University of Chicago Michael Grant; Ohio University noah bluestone; Boston University Ruth McKenzie; Boston University William Kremen; University of California San Diego and VA SD Center of Excellence for Stress and Mental Health Hong Xian; Washington University School of Medicine
Presented by: Michael Lyons, Boston University
Session 19: ADHD and autism June 19, 2015 16:00 to 17:15 Gaslamp Room
Session Chair: Valerie Knopik, Division of Behavior Genetics, RI Hospital/Brown University
1. Parental asthma and maternal asthma medication during pregnancy and risk of offspring autism spectrum disorder
By Tong Gong; Karolinska Institutet Cecilia Lundholm; Karolinska Institutet Gustaf Rejnö; Karolinska Institutet Sven Bölte; Karolinska Institutet Henrik Larsson; Karolinska Institutet Brian D'Onofrio; Indiana University-Bloomington Paul Lichtenstein; Karolinska Institutet Catarina Almqvist; Karolinska Institutet
Presented by: Tong Gong, Karolinska Institutet
(Thompson Award Candidate)
2. Whole genome sequencing identifies balanced and complex de novo structural variation in autism
By William Brandler; University of California, San Diego
Presented by: William Brandler, University of California, San Diego
(Thompson Award Candidate)
3. Relative immaturity and attention problems; A longitudinal, multi-informant twin study
By Isabell Brikell; Karolinska Institutet Ralf Kuja-Halkola; Karolinska Institutet Jan-Olov Larsson; Karolinska Institutet Paul Lichtenstein; Karolinska Institutet Per-Anders Rydelius; Karolinska Institutet Henrik Larsson; Karolinska Institutet
Presented by: Isabell Brikell, Karolinska Institutet
(Thompson Award Candidate)
4. Smoking during pregnancy and ADHD risk: A genetically-informed, multiple-rater approach
By Valerie Knopik; Division of Behavior Genetics, RI Hospital/Brown University Kristine Marceau; Brown University and Rhode Island Hospital Rohan Palmer; Division of Behavioral Genetics, Rhode Island Hospital & Brown University Taylor Smith; Division of Behavioral Genetics, Rhode Island Hospital & Brown University Andrew Heath; Washington University School of Medicine
Presented by: Valerie Knopik, Division of Behavior Genetics, RI Hospital/Brown University
Session 20: Childhood psychopathology June 19, 2015 17:30 to 18:30 Salon A/B
Session Chair: Irwin Waldman, Emory University
1. Testing Alternative Models for the Underlying Structure of Childhood Psychopathology using Confirmatory Factor Analyses and Multivariate Behavior Genetic Analyses
By Irwin Waldman; Emory University Paul Rathouz; University of Wisconsin, Madison Carol Van Hulle; University of Wisconsin-Madison Benjamin Lahey; University of Chicago
Presented by: Irwin Waldman, Emory University
2. Familiality of the association between attention-deficit/hyperactivity disorder and borderline personality disorder
By Ralf Kuja-Halkola; Karolinska Institutet Henrik Larsson; Karolinska Institutet Paul Lichtenstein; Karolinska Institutet
Presented by: Ralf Kuja-Halkola, Karolinska Institutet
3. The general factor of psychopathology in childhood and maladaptive outcomes in young adulthood: A Swedish population twin study
By Erik Pettersson; Karolinska Institutet Benjamin Lahey; University of Chicago Henrik Larsson; Karolinska Institutet Sebastian Lundström; Gothenburg University Paul Lichtenstein; Karolinska Institutet
Presented by: Erik Pettersson, Karolinska Institutet
Session 21: New aspects of methods June 19, 2015 17:30 to 18:30 Salon C
Session Chair: Carol Prescott, University of Southern California
1. MIDDLE: A new paradigm for genetic studies.
By Michael Neale; Virginia Commonwealth University Michael Hunter; University of Oklahoma Health Sciences Center Hermine Maes; Virginia Commonwealth University Timo von Oertzen; University of Virginia Steve Boker; University of Virginia
Presented by: Michael Neale, Virginia Commonwealth University
2. Biases in genetic variance estimates induced by assortative mating
By Teresa de Candia; University of Colorado at Boulder Rasool Tahmasbi; University of Colorado, Boulder Greg Carey; University of Colorado Lindon Eaves; VIPBG, Virginia Commonwealth University Matt Jones; University of Colorado, Boulder Matthew Keller; University of Colorado at Boulder
Presented by: Teresa de Candia, University of Colorado at Boulder
3. Developmentally Dynamic Intra-individual Variations in Heritability of Physical Aggression during Infancy: Some SEM Models
By Eric Lacourse; Université de Montréal
Presented by: Eric Lacourse, Université de Montréal
4. Validation of Zygosity Classification in the Project Talent Twin and Sibling Study
By Carol Prescott; University of Southern California Deanna Lyter Achorn; American Institutes for Research Randy Bautista; University of Southern California Franchesca Cortez; University of Southern California John McArdle; University of Southern California Susan Lapham; American Institutes for Research
Presented by: Carol Prescott, University of Southern California
Session 22: Genes and society June 19, 2015 17:30 to 18:30 Gaslamp Room
Session Chair: Scott Vrieze, University of Michigan
1. Genes, Psychological Traits, and Voter Turnout
By Christopher Dawes; New York University
Presented by: Christopher Dawes, New York University
2. Genes for Good: Citizen Science and Participant Values
By Maia Frieser; University of Colorado Boulder David Brazel; University of Colorado Boulder Johanna Forster; University of Michigan Kevin Li; University of Michigan Gregory Zajac; University of Michigan Katharine Brieger; University of Michigan Goncalo Abecasis; University of Michigan Scott Vrieze; University of Michigan
Presented by: Maia Frieser, University of Colorado Boulder
(Thompson Award Candidate)
3. Genetic correlates of non-participation in a population cohort
By Joanna Martin; Broad Institute Kate Tilling; Bristol University Leon Hubbard; Cardiff University Evie Stergiakouli; Bristol University Michael O'Donovan; Cardiff University George Davey Smith; Bristol University Anita Thapar; Cardiff University Stanley Zammit; Cardiff University
Presented by: Joanna Martin, Broad Institute
Session 23: Symposium: Neuroimaging and Genetics, part I June 20, 2015 8:45 to 9:45 Salon A/B
Elucidating brain genetics is critical to behavior genetics. We present twin and genome-wide association study (GWAS) investigations of the genetics of brain structure and brain-behavior relationships. Presentations are organized around three themes across two sessions. Theme 1 – Polygenicity of the Cortex: Presenters will address the highly polygenic nature of cortical architecture, its relationship to behavior, and variation as a function of evolutionarily conserved or expanded regions. GWAS data from multiple studies will be presented on the additive effects of single nucleotide polymorphisms (SNPs) on relative surface area (SA) across cortical regions (Chen). Vietnam Era Twin Study of Aging (VETSA) data will be presented on the complex relationship of general cognitive ability to relative cortical SA and relative cortical thickness (CT) (Vuoksimaa). Brisbane Longitudinal Twin Study (BLTS) and Queensland Twin Imaging (QTIM) study data will be presented on the relationship of anxiety-depression to SA and CT (Couvy-Duchesne). Theme 2 – Genetic Variants Identified in Large-Scale GWASs: ENIGMA data will be presented on genes that influence gray matter structures and their overlap with neurological and psychiatric disorders (Medland), and genes that influence the integrity of white matter microstructure based on diffusion tensor imaging (Jahanshad). Theme 3 – Age-Related Differences and Plasticity: Presenters will address the understudied issues of similarities and differences of genetic patterning of brain regions at different ages, and genetic influences on structural brain changes over time. The genetic patterning of cortical regions based on CT will be examined in QTIM young adults to determine similarity with the pattern observed in VETSA middle-aged adults an average of 35 years older (Strike). ENIGMA twin data will be presented on genetic influences on age-related change in subcortical volumes into late adulthood (Hulshoff Pol). NIMH twin data will be presented on change in genetically-mediated correlations between cortical regions throughout childhood and adolescence (Schmitt). The two sessions will be followed by discussant, David Glahn.
Session Chair: William Kremen, University of California San Diego and VA SD Center of Excellence for Stress and Mental Health
1. Polygenic architecture of human cortical surface area
By Chi-Hua Chen; University of California San Diego
Presented by: Chi-Hua Chen, University of California San Diego
2. Configuration of cortical surface area and thickness and general cognitive ability
By Eero Vuoksimaa; University of Helsinki Matthew Panizzon; University of California San Diego Chi-Hua Chen; University of California San Diego Mark Fiecas; University of California San Diego Christine Fennema-Notestine; University of California San Diego Lisa Eyler; MIRECC, VA San Diego Healthcare System and University of California San Diego Carol Franz; University of California San Diego Michael Lyons; Boston University anders Dale; University of California San Diego William Kremen; University of California San Diego and VA SD Center of Excellence for Stress and Mental Health
Presented by: Eero Vuoksimaa, University of Helsinki
3. Non-linear association of anxiety-depression (SPHERE) score with cortical surface and surface area
By Baptiste Couvy-Duchesne; QIMR Berghofer Medical Research Institute Lachlan Strike; QIMR Berghofer Medical Research Institute Paul Thompson; Imaging Genetics Center, Keck School of Medicine of USC Katie McMahon; Center for Advanced Imaging, the University of Queensland Greig de Zubicaray; School of Psychology, the University of Queensland Nick G. Martin; QIMR Berghofer Medical Research Institute Ian Hickie; Brain and Mind Research Institute, the University of Sydney Margaret Wright; Queensland Institute of Medical Research
Presented by: Baptiste Couvy-Duchesne, QIMR Berghofer Medical Research Institute
(Thompson Award Candidate)
4. Identifying genetic variants influencing brain structure: recent results from the ENIGMA consortium
By Sarah Medland; QIMR Berghofer Medical Research Institute
Presented by: Sarah Medland, QIMR Berghofer Medical Research Institute
Session 24: Academic development June 20, 2015 8:45 to 9:45 Salon C
Session Chair: Jonathan Beauchamp, Harvard University
1. Genetic and environmental underpinnings of spatial abilities and their role in predicting academic achievement and success in STEM
By Kaili Rimfeld; King's College London Nicholas Shakeshaft; King's College London Kerry Schofield; King's College London Margherita Malanchini; Goldsmiths College Maja Rodic; Laboratory for Cognitive Investigations and Behavioral Genetics, Tomsk State University Yulia Kovas; Goldsmiths College Robert Plomin; Kings College London
Presented by: Kaili Rimfeld, King's College London
(Thompson Award Candidate)
2. Pleiotropy with Educational Attainment: Results Based on a GWAS with 300,000 Individuals
By Jonathan Beauchamp; Harvard University Daniel Benjamin; Cornell University David Cesarini; New York University Ronald de Vlaming; Erasmus University Rotterdam Tonu Esko; Estonian Genome Center Mark Fontana; University of Michigan Philipp Koellinger; University of Amsterdam Aysu Okbay; Erasmus University Rotterdam Cornelius Rietveld; Erasmus University Rotterdam Patrick Turley; Harvard University
Presented by: Jonathan Beauchamp, Harvard University
3. Biological insights from 73 genetic loci associated with educational attainment
By Aysu Okbay; Erasmus University Rotterdam Tonu Esko; Estonian Genome Center Mark Fontana; University of Michigan Patrick Turley; Harvard University Jonathan Beauchamp; Harvard University Cornelius Rietveld; Erasmus University Rotterdam Fleur Meddens; University of Amsterdam Philipp Koellinger; University of Amsterdam Daniel Benjamin; Cornell University David Cesarini; New York University
Presented by: Aysu Okbay, Erasmus University Rotterdam
(Thompson Award Candidate)
4. Associations Between Dimensions of Psychosocial Stress and Cognitive Performance in a Diverse Twin Sample
By Laura Engelhardt; University of Texas at Austin Daniel Briley; University of Texas at Austin Kathryn Harden; University of Texas at Austin Elliot Tucker-Drob; University of Texas at Austin
Presented by: Laura Engelhardt, University of Texas at Austin
(Thompson Award Candidate)
Session 25: Symposium: Neuroimaging and Genetics, part II June 20, 2015 10:05 to 11:20 Salon A/B
Session Chair: William Kremen, University of California San Diego and VA SD Center of Excellence for Stress and Mental Health
1. ENIGMA-DTI: the genetic contributions to white matter microstructure
By Neda Jahanshad; Imaging Genetics Center, Keck School of Medicine of USC
Presented by: Neda Jahanshad, Imaging Genetics Center, Keck School of Medicine of USC
2. Genetic contributions to cortical thickness patterning in young adults
By Lachlan Strike; QIMR Berghofer Medical Research Institute Baptiste Couvy-Duchesne; QIMR Berghofer Medical Research Institute Katie McMahon; Center for Advanced Imaging, the University of Queensland Greig de Zubicaray; School of Psychology, the University of Queensland Paul Thompson; Imaging Genetics Center, Keck School of Medicine of USC Nick G. Martin; QIMR Berghofer Medical Research Institute Margaret Wright; Queensland Institute of Medical Research
Presented by: Lachlan Strike, QIMR Berghofer Medical Research Institute
(Thompson Award Candidate)
3. Genetic influences on longitudinal changes in subcortical volumes: results of the ENIGMA Plas-ticity Working Group
By Hilleke Hulshoff Pol; University Medical Center Utrecht Rachel Brouwer; University Medical Center Utrecht David Glahn; Department of Psychiatry, Yale University of Medicine Derrek Hibar; Imaging Genetics Center, Keck School of Medicine of USC Xue Hua; Imaging Genetics Center, Keck School of Medicine of USC Neda Jahanshad; Imaging Genetics Center, Keck School of Medicine of USC Lucija Abramovic; University Medical Center Utrecht Carol Franz; University of California San Diego Narelle Hansell; Queensland Institute of Medical Research Marinka Koenis; University Medical Center Utrecht Karen Mather; Centre for Healthy Brain Ageing, Psychiatry, University of New South Wales, Sydney Matthew Panizzon; University of California San Diego Lachlan Strike; Neuroimaging Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Queensland Suzanne Swagerman; VU University Amsterdam Anbupalam Thalamuthu; Centre for Healthy Brain Ageing, Psychiatry, University of New South Wales, Sydney Wei Wen; Centre for Healthy Brain Ageing, Psychiatry, University of New South Wales, Sydney Dorret Boomsma; VU Amsterdam John Gilmore; Department of Psychiatry, University of North Carolina-Chapel Hill Nitin Gogtay; National Institute of Mental Health, National Institutes of Health Rene S Kahn; Rudolf Magnus Institute of Neuroscience, University Medical Centre Utrecht, Department of Psychiatry William Kremen; University of California San Diego and VA SD Center of Excellence for Stress and Mental Health Perminder Sachdev; University of New South Wales Margaret Wright; Queensland Institute of Medical Research Paul Thompson; Imaging Genetics Center, Keck School of Medicine of USC
Presented by: Hilleke Hulshoff Pol, University Medical Center Utrecht
4. Genetically-Informative Multivariate Models of Brain Maturation
By James Schmitt; University of Pennsylvania Jay Giedd; UCSD Michael Neale; Virginia Commonwealth University
Presented by: James Schmitt, University of Pennsylvania
Discussant:   David Glahn, Department of Psychiatry, Yale University of Medicine
Session 26: Development and substance use June 20, 2015 10:05 to 11:20 Salon C
Session Chair: Antti Latvala, University of Helsinki
1. Child Language Development and Later Alcohol Use Behaviors
By Kerri Woodward Robin Corley; University of Colorado Boulder Naomi Friedman; University of Colorado Boulder Alexander Hatoum; University of Colorado, Boulder John Hewitt; University of Colorado Boulder Brooke Huibregtse; University of Colorado at Boulder, Institute for Behavioral Genetics Soo Rhee; University of Colorado Michael Stallings; University of Colorado
Presented by: Kerri Woodward,
(Thompson Award Candidate)
2. Cognitive ability and risk for substance misuse: Investigating the link in Swedish nationwide family data
By Antti Latvala; University of Helsinki Ralf Kuja-Halkola; Karolinska Institutet Henrik Larsson; Karolinska Institutet Paul Lichtenstein; Karolinska Institutet
Presented by: Antti Latvala, University of Helsinki
3. Modeling etiology of drug abuse in Swedish twins, full siblings, half siblings, cousins and step siblings.
By Hermine Maes; Virginia Commonwealth University Michael Neale; Virginia Commonwealth University Henrik Ohlson; Lund University Jan Sundquist; Lund University Kristina Sundquist; Lund University Kenneth Kendler; VCU-VIPBG
Presented by: Hermine Maes, Virginia Commonwealth University
4. A Biometric and Genome-Wide Association Analysis of Alcohol Use Patterns from Early Adolescence to Young Adulthood
By Jeanne Savage; Virginia Commonwealth University Jaakko Kaprio; University of Helsinki Richard Rose; Indiana University Antti Latvala; University of Helsinki Anu Loukola; University of Helsinki Danielle Dick; Virginia Commonwealth University
Presented by: Jeanne Savage, Virginia Commonwealth University
(Thompson Award Candidate)
Session 27: Depression June 20, 2015 10:05 to 11:20 Gaslamp Room
Session Chair: S. Alexandra Burt, Michigan State University
1. A Direct Test of the Diathesis-Stress Hypothesis Using Polygenic Risk Scores
By Nick G. Martin; QIMR Berghofer Medical Research Institute Baptiste Couvy-Duchesne; QIMR Berghofer Medical Research Institute Lucía Colodro Conde; QIMR Berghofer Medical Research Institute Gu Zhu; QIMR Berghofer Medical Research Institute William Coventry; University of New England Sarah Medland; QIMR Berghofer Medical Research Institute
Presented by: Nick G. Martin, QIMR Berghofer Medical Research Institute
2. Gene-by-Environment Interactions, Social Stress, and Depression in Older Adults
By Jaime Derringer; University of Illinois at Urbana-Champaign Mark Whisman; University of Colorado Boulder
Presented by: Jaime Derringer, University of Illinois at Urbana-Champaign
3. Do ‘Plasticity’ Genes Relate to Sensitivity to the Environment? Divergence in Depression Scores in Monozygotic Twin Pairs
By Sarah Moore; Cornell University Jane Mendle; Cornell University
Presented by: Sarah Moore, Cornell University
(Thompson Award Candidate)
4. A straightforward family design for examining the contribution of mitochondrial DNA to psychiatric/behavioral phenotypes
By S. Alexandra Burt; Michigan State University Kelly Klump; Michigan State University Qing Lu; Michigan State University
Presented by: S. Alexandra Burt, Michigan State University
Session 28: Genes, epigenetics and substance use June 20, 2015 13:45 to 15:00 Salon A/B
Session Chair: Jaakko Kaprio, University of Helsinki
1. Examining the relationship between FTND, CPD and rs16969968 with different psychometric models
By Brad Verhulst; Virginia Institute of Psychiatric and Behavioral Genetics Michael Neale; Virginia Commonwealth University Jingchun Chen; VIPBG, Virginia Commonwealth University Xiangning Chen; VIPBG, Virginia Commonwealth University
Presented by: Brad Verhulst, Virginia Institute of Psychiatric and Behavioral Genetics
2. Deep sequencing of 71 genes to detect variation associated with alcohol dependence
By Shaunna Clark; Virginia Commonwealth University Joseph McClay; Virginia Commonwealth University Daniel Adkins; Virginia Commonwealth University Karolina Aberg; Virginia Commonwealth University Gaurav Kumar; Virginia Commonwealth University Srilaxmi Nerella; Virginia Commonwealth Univeristy Linying Xie; Virginia Commonwealth University Ann Collins; University of North Carolina, Chapel Hill James Crowley; University of North Carolina, Chapel Hill Corey Quakenbush; University of North Carolina, Chapel Hill Chris Hillard; University of North Carolina, Chapel Hill Guimin Gao; Virginia Commonwealth University Andrey Shabalin; Virginia Commonwealth University Scott Vrieze; University of Michigan Roseann Peterson; Virginia Commonwealth University William Copeland; Duke University Judy Silberg; Virginia Commonwealth University Matthew McGue; University of Minnesota Hermine Maes; Virginia Commonwealth University William Iacono; University of Minnesota Patrick Sullivan; University of North Carolina E. Jane Costello; Duke University Edwin van den Oord; Virginia Commonwealth University
Presented by: Shaunna Clark, Virginia Commonwealth University
3. VALIDATING THE ASSUMPTION OF GENETIC HOMOGENEITY ACROSS DSM-IV INDICATORS OF ALCOHOL DEPENDENCE
By Rohan Palmer; Division of Behavioral Genetics, Rhode Island Hospital & Brown University John McGeary; Providence VAMC/Brown University Andrew Heath; Washington University School of Medicine Matthew Keller; University of Colorado at Boulder Valerie Knopik; Rhode Island Hospital
Presented by: Rohan Palmer, Division of Behavioral Genetics, Rhode Island Hospital & Brown University
4. Examining Gene-Environment interactions with Classical Twin Models and Epigenetic Analysis
By Jane Ebejer; Virginia Institute for Psychiatric and Behavior Genetics Tim York; VCU Richard Rose; Indiana University Richard Viken; Indiana University Jaakko Kaprio; University of Helsinki Danielle Dick; Virginia Commonwealth University
Presented by: Jane Ebejer, Virginia Institute for Psychiatric and Behavior Genetics
5. DNA Methylation Signatures in MZ Twins Discordant for Smoking
By Brinda Rana Matthew Panizzon; University of California San Diego Carol Franz; University of California San Diego William Kremen; University of California San Diego and VA SD Center of Excellence for Stress and Mental Health
Presented by: Brinda Rana,
Session 29: Women's health June 20, 2015 13:45 to 15:00 Salon C
Session Chair: Brian D'Onofrio, Indiana University
1. Changes in Genetic Risk for Emotional Eating across the Menstrual Cycle: A Longitudinal Study
By Kelly Klump; Michigan State University Britny Hildebrandt; Michigan State University Shannon O'Connor; Michigan State University Pamela Keel; Florida State University Michael Neale; Virginia Commonwealth University Cheryl Sisk; Michigan State University Steven Boker; University of Virginia S. Alexandra Burt; Michigan State University
Presented by: Kelly Klump, Michigan State University
2. High heritability estimates for Nausea and Vomiting during Pregnancy
By Lucía Colodro Conde; QIMR Berghofer Medical Research Institute Patrick Jern; Åbo Akademi University Ada Johansson; QIMR Berghofer Medical Research Institute Juan Ordonana; University of Murcia Sarah Medland; QIMR Berghofer Medical Research Institute
Presented by: Lucía Colodro Conde, QIMR Berghofer Medical Research Institute
3. Maternal Body Mass Index and Offspring Fetal Growth: A Cousin- and Sibling-Comparison Study
By Brian D'Onofrio; Indiana University Anna Oberg; Harvard School of Public Health Quetzal Class; Indiana University Martin Rickert; Indiana University Lauren Bramson; Indiana University, Bloomington Catarina Almqvist; Karolinska Institutet Henrik Larsson; Karolinska Institutet Paul Lichtenstein; Karolinska Institutet
Presented by: Brian D'Onofrio, Indiana University
4. A Genetically Informed Study of the Associations between Maternal Age at Childbearing and Adverse Perinatal Outcomes
By Ayesha Sujan; Indiana University Martin Rickert; Indiana University Quetzal Class; Indiana University Claire Coyne; Indiana University Paul Lichtenstein; Karolinska Institutet Catarina Almqvist Malmros; Karolinska Institutet Henrik Larsson; Karolinska Institutet Arvid Sjolander; Karolinska Institutet Benjamin Lahey; University of Chicago Carol Van Hulle; University of Wisconsin-Madison Irwin Waldman; Emory University Anna Oberg; Harvard School of Public Health Brian D'Onofrio; Indiana University
Presented by: Ayesha Sujan, Indiana University
(Thompson Award Candidate)
Session 30: Executive functioning June 20, 2015 13:45 to 15:00 Gaslamp Room
Session Chair: John Hewitt, University of Colorado Boulder
1. Genetic Variance In Executive Functioning Accounts for some of the Comorbidity in Internalizing and Externalizing Behavior
By Alexander Hatoum; University of Colorado, Boulder Soo Rhee; University of Colorado Robin Corley; University of Colorado Boulder John Hewitt; University of Colorado Boulder Naomi Friedman; University of Colorado Boulder
Presented by: Alexander Hatoum, University of Colorado, Boulder
(Thompson Award Candidate)
2. Predicting neural correlates of executive functioning with genetic risk scores for psychiatric disorders
By Chelsie Benca Jaime Derringer; University of Illinois at Urbana-Champaign Robin Corley; University of Colorado Boulder John Hewitt; University of Colorado Boulder Naomi Friedman; University of Colorado Boulder
Presented by: Chelsie Benca,
(Thompson Award Candidate)
3. Stability and Change in the Relations Among Executive Functions and Substance Use and Dependence From Late Adolescence to Early Adulthood
By Naomi Friedman; University of Colorado Boulder Daniel Gustavson; University of Colorado Boulder Robin Corley; University of Colorado Boulder Michael Stallings; University of Colorado John Hewitt; University of Colorado Boulder
Presented by: Naomi Friedman, University of Colorado Boulder
4. Understanding the Cognitive and Genetic Underpinnings of Procrastination: Evidence for Shared Genetic Influences with Goal Management and Executive Function Abilities
By Daniel Gustavson; University of Colorado Boulder Akira Miyake; University of Colorado Boulder John Hewitt; University of Colorado Boulder Naomi Friedman; University of Colorado Boulder
Presented by: Daniel Gustavson, University of Colorado Boulder
Session 31: Symposium: Novel Methods and Recent Results for Enrichment and Pleiotropy in GWAS June 20, 2015 15:20 to 16:30 Salon A/B
Complex traits and disorders such as schizophrenia are multifactorial and associated with the effects of multiple genes in combination with environmental factors. These disorders often cluster in families, have no clear-cut pattern of inheritance, and have a high fraction of phenotypic variance attributable to genetic variance (high heritability). It is becoming increasingly clear that many genes influence most complex traits and disorders. In such a scenario with a very high number of risk genes (‘polygenic’), each gene has a tiny effect. This makes it difficult to determine an individual’s risk, and to identify disease mechanisms that can be used for development of new effective treatments. Genome-wide association studies (GWAS) have identified many trait-associated single nucleotide polymorphisms (SNPs), but so far these explain only small portions of the heritability of complex disorders. This “missing heritability” has been attributed to a number of potential causes, including lack of typing of rare variants. However, it has been shown that a large proportion of the missing heritability is available within GWAS data when associations of SNPs are examined in aggregate. This implies the existence of numerous common variants with small genetic (‘polygenic’) effects. These effects cannot be reliably detected with traditional GWAS statistical methods given current sample sizes. Thus, there is a need for innovative statistical approaches to identify polygenetic effects and reduce the proportion of ‘missing heritability’. In this symposium, the speakers will describe recent empirical results and novel statistical tools for understanding the roles of linkage disequilibrium, enrichment factors (such as functional genic annotations), and pleiotropy in genome-wide association studies.
Session Chair: Wesley Thompson, University of California San Diego
1. An Empirical Bayes Approach to Estimating GWAS Effect Sizes
By Wesley Thompson; University of California San Diego
Presented by: Wesley Thompson, University of California San Diego
2. Leveraging genome-wide association analysis to estimate genetic correlation
By Benjamin Neale; Massachusetts General Hospital
Presented by: Benjamin Neale, Massachusetts General Hospital
3. Examining Multiple Sources of “Enrichment” in GWAS Statistics
By Andrew Schork; UC San Diego
Presented by: Andrew Schork, UC San Diego
(Thompson Award Candidate)
4. Case studies in pathway enrichment analysis for genome-wide association studies: successes, limitations, and future directions
By Peter Carbonetto; Ancestry.com
Presented by: Peter Carbonetto, Ancestry.com
Discussants:      1 Michael Neale, Virginia Commonwealth University      2 Nicholas Schork, Scripps Translational Sciences Institute
Session 32: Externalizing June 20, 2015 15:20 to 16:30 Salon C
Session Chair: Meike Bartels, VU University Amsterdam
1. Trait Endophenotypes for Antisocial Behavior: Evidence for Novelty & Sensation Seeking Across Two Independent Samples
By Frank Mann; University of Texas at Austin Megan Patterson; University of Texas at Austin Nicholas MARTIN; Queensland Institute of Medical Research Elliot Tucker-Drob; University of Texas at Austin Kathryn Harden; University of Texas at Austin
Presented by: Frank Mann, University of Texas at Austin
(Thompson Award Candidate)
2. Genetic and environmental influences on the development of impulsivity and disruptive behavior
By Elizabeth Long; Virginia Commonwealth University Judy Silberg; Virginia Commonwealth University Lindon Eaves; VIPBG, Virginia Commonwealth University Nathan Gillespie; VIPBG
Presented by: Elizabeth Long, Virginia Commonwealth University
(Thompson Award Candidate)
3. Comparing sum score and item-level models in an investigation of stability and change of heritability of physical aggression in Dutch twins from age 3 to age 16
By Daniel McArtor; University of Notre Dame Meike Bartels; VU University Amsterdam Dorret Boomsma; VU Amsterdam Gitta Lubke; University of Notre Dame, VU University Amsterdam
Presented by: Daniel McArtor, University of Notre Dame
4. Genetic and Environmental Influences on Antisocial Behavior Sub-Types: Moderation by Age and Puberty
By Kathryn Harden; University of Texas at Austin Megan Patterson; University of Texas at Austin Jennifer Tackett; University of Houston Elliot Tucker-Drob; University of Texas at Austin
Presented by: Kathryn Harden, University of Texas at Austin

This program was last updated on 2015-06-16 0:20:25 EDT